Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 1.00 |
| ▸ | EGFR | P00533 | 5/20 | 0.68 |
| ▸ | LCK | P06239 | 2/20 | 0.68 |
| ▸ | ITK | Q08881 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075029 | 1.00 | BTK (1.00) | BTKEGFRLCKITK | |
| SCHEMBL16075013 | 0.95 | BTK (1.00) | BTKEGFRLCKITK | |
| SCHEMBL20144266 | 0.93 | BTK (0.87) | BTKEGFRLCKITK | |
| SCHEMBL20144265 | 0.93 | BTK (0.87) | BTKEGFRLCKITK | |
| SCHEMBL20144247 | 0.90 | BTK (0.81) | BTKEGFRLCKITK | |
| SCHEMBL20144230 | 0.90 | BTK (0.84) | BTKEGFRLCKITK | |
| SCHEMBL20144232 | 0.88 | BTK (0.82) | BTK | |
| SCHEMBL20144248 | 0.88 | BTK (0.82) | BTK | |
| SCHEMBL20144244 | 0.88 | BTK (0.78) | BTKEGFRLCKITK | |
| SCHEMBL20144234 | 0.88 | BTK (0.78) | BTKEGFRLCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940893-B2 | Heteroaromatic compounds as BTK inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-8940893-B2 | Heteroaromatic compounds as BTK inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-20140275014-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140275014-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275014-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LYN | BTK 1/4885EGFR 239/4885LCK 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.