Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.78 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | ITK | Q08881 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144244 | 1.00 | BTK (0.78) | BTKEGFRLCKITK | |
| SCHEMBL20144235 | 1.00 | BTK (0.78) | BTKEGFRLCKITK | |
| SCHEMBL20144247 | 0.91 | BTK (0.81) | BTKEGFRLCKITK | |
| SCHEMBL20144265 | 0.90 | BTK (0.87) | BTKEGFRLCKITK | |
| SCHEMBL20144266 | 0.90 | BTK (0.87) | BTKEGFRLCKITK | |
| SCHEMBL16075029 | 0.88 | BTK (1.00) | BTKEGFRLCKITK | |
| SCHEMBL16074996 | 0.88 | BTK (1.00) | BTKEGFRLCKITK | |
| SCHEMBL20144232 | 0.84 | BTK (0.82) | BTK | |
| SCHEMBL20144248 | 0.84 | BTK (0.82) | BTK | |
| SCHEMBL16075013 | 0.83 | BTK (1.00) | BTKEGFRLCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970300-B1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-05-16 | — | — | EP | disclosed |