Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 11/20 | 0.39 |
| ▸ | NEK2 | P51955 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075480 | 0.89 | KDM4E (0.39) | DHPSKDM4EKMT2ATP53RAB9A | |
| SCHEMBL16075403 | 0.87 | MAP4K4 (0.43) | DHPSNEK2HSD17B10 | |
| SCHEMBL1396987 | 0.84 | DHPS (0.51) | DHPSNEK2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL16075514 | 0.84 | DHPS (0.53) | DHPSCYP1A1CYP1A2CYP1B1KDM4E | |
| SCHEMBL16075419 | 0.83 | DHPS (0.52) | DHPSNEK2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL16075438 | 0.83 | DHPS (0.52) | DHPSNEK2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1397030 | 0.83 | DHPS (0.54) | DHPSNEK2KDM4EKMT2ADPP4 | |
| SCHEMBL16075412 | 0.81 | DHPS (0.37) | DHPSNEK2RAB9A | |
| SCHEMBL1396924 | 0.80 | DPP4 (0.44) | DHPSKDM4EDPP4TP53 | |
| SCHEMBL16075447 | 0.78 | CHRNA7 (0.46) | DHPSCYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2019-02-13 | — | — | EP | disclosed |
| US-9113629-B2 | 4-amino-6-(4-substituted-phenyl)-picolinates and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-9113629-B2 | 4-amino-6-(4-substituted-phenyl)-picolinates and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-08-25 | — | — | US | disclosed |
| WO-2014150850-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140274696-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274696-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140274696-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, P2RX6, ABAT | DHPS 1389/4885NEK2 2126/4885CYP1A1 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.