Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075825 | 0.93 | MEN1 (0.54) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL16075823 | 0.88 | MEN1 (0.47) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL18829074 | 0.86 | MEN1 (0.51) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL18313861 | 0.81 | MEN1 (0.51) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL13609836 | 0.80 | USP2 (0.52) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL20288667 | 0.79 | MEN1 (0.50) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL17532633 | 0.79 | MEN1 (0.51) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL17693122 | 0.78 | MEN1 (0.50) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL20286054 | 0.77 | MEN1 (0.48) | MEN1KMT2ABLMPOLBUSP2 | |
| SCHEMBL20288665 | 0.77 | FPR2 (0.41) | MEN1KMT2ABLMPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160202247-A1 | PHOTO-PATTERNABLE OPTICAL LUMINESCENCE DUAL SENSORS AND METHODS OF PREPARING AND USING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-14 | — | — | US | disclosed |
| US-20140273043-A1 | TRI-COLOR DUAL GLUCOSE AND OXYGEN SENSORS AND METHODS OF PREPARING AND USING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-09-18 | — | — | US | disclosed |