Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061137 | 0.82 | THRB (0.42) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL9278178 | 0.78 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL22395412 | 0.78 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL25303278 | 0.78 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL5709983 | 0.78 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL25389134 | 0.78 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL13785396 | 0.78 | THRB (0.34) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL13785395 | 0.78 | THRB (0.34) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL1164867 | 0.75 | THRB (0.62) | THRBUSP2CYP3A4SMN1; SMN2ACACB | |
| SCHEMBL13849903 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216403-B2 | Epoxy chemistry derived materials as reversed-phase and hydrophobic interaction chromatography media, method for their synthesis and use | DIONEX CORPORATION (US) | 2015-12-22 | — | — | US | disclosed |
| US-20140260563-A1 | EPOXY CHEMISTRY DERIVED MATERIALS AS REVERSED-PHASE AND HYDROPHOBIC INTERACTION CHROMATOGRAPHY MEDIA, METHOD FOR THEIR SYNTHESIS AND USE | DIONEX CORPORATION | 2014-09-18 | — | — | US | disclosed |