SCHEMBL16077429

SCHEMBL16077429

Cc1ccc(-c2snc(Cl)c2COc2ccc(CCC(=O)O)c(C)c2C)cc1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16048486 0.94 FFAR4 (0.84) FFAR4
SCHEMBL16049000 0.93 FFAR4 (0.82) FFAR4
SCHEMBL16048676 0.92 FFAR4 (0.81) FFAR4
SCHEMBL16048727 0.91 FFAR4 (0.80) FFAR4
SCHEMBL16048988 0.91 FFAR4 (1.00) FFAR4
SCHEMBL16049019 0.91 FFAR4 (0.88) FFAR4
SCHEMBL16048923 0.90 FFAR4 (0.77) FFAR4
SCHEMBL16049367 0.87 FFAR4 (0.73) FFAR4
SCHEMBL16048434 0.84 FFAR4 (0.69) FFAR4
SCHEMBL16048875 0.84 FFAR4 (0.72) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067898-B1 Isothiazole derivatives as GPR120 agonists for the treatment of type II diabetes JANSSEN PHARMACEUTICA NV (BE) 2015-06-30 US disclosed
US-20140275179-A1 GPR120 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES JANSSEN PHARMACEUTICA NV (BE) 2014-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275179-A1 GPR120 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES GPR119, GLP1R, GCGR FFAR4 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.