Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13248185 | 0.87 | HPGD (0.50) | HPGDPOLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL13248187 | 0.87 | HPGD (0.52) | HPGDPOLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL13248184 | 0.85 | HPGD (0.50) | HPGDPOLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL13248190 | 0.83 | HPGD (0.56) | HPGDPOLBKDM4EMEN1KMT2A | |
| SCHEMBL18611642 | 0.81 | HPGD (0.49) | HPGDLMNAKDM4EALDH1A1HDAC3 | |
| SCHEMBL1754953 | 0.80 | HPGD (0.46) | HPGDPOLBLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL25449 | 0.78 | MAPK1 (0.57) | HPGDPOLBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL15298144 | 0.77 | HPGD (0.50) | HPGDLMNAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13248194 | 0.77 | HPGD (0.41) | HPGDPOLBHDAC3HDAC4HDAC1 | |
| SCHEMBL18059269 | 0.76 | MAPT (0.54) | HPGDLMNAKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140267672-A1 | DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY | VENTANA MEDICAL SYSTEMS, INC. | 2014-09-18 | — | — | US | disclosed |
| US-20140267672-A1 | DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY | VENTANA MEDICAL SYSTEMS, INC. | 2014-09-18 | — | — | US | disclosed |