Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13248194 | 0.83 | HPGD (0.41) | HPGDBCHEHDAC3HDAC4HDAC1 | |
| SCHEMBL16077518 | 0.81 | HPGD (0.54) | HPGDALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL13248190 | 0.78 | HPGD (0.56) | HPGDTDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL14688254 | 0.78 | HPGD (0.46) | HPGDALDH1A1LMNA | |
| SCHEMBL13740181 | 0.76 | TDP1 (0.47) | NPSR1ALDH1A1GFERTDP1HDAC3 | |
| SCHEMBL14687749 | 0.76 | HPGD (0.51) | HPGDNPSR1ALDH1A1TDP1HDAC3 | |
| SCHEMBL19442573 | 0.75 | BCHE (0.45) | NPSR1BCHEHDAC1LMNA | |
| SCHEMBL13248184 | 0.75 | HPGD (0.50) | HPGDALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL1555895 | 0.75 | DYRK1A (0.43) | HPGDALDH1A1 | |
| SCHEMBL17540251 | 0.71 | RET (0.44) | NPSR1ALDH1A1TDP1BCHEHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040349-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2017-03-09 | — | — | WO | disclosed |