SCHEMBL16077971

SCHEMBL16077971

CC(C)(C)c1cccc(-c2cccc(-c3cccc(C(C)(C)C)n3)n2)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.44
CCR8 P51685 2/20 0.44
IDH1 O75874 6/20 0.42
IDH2 P48735 1/20 0.42
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
ALPL P05186 1/20 0.41
HSP90AA1 P07900 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
CCR5 P51681 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31084593 0.97 CCR1 (0.46) CCR1CCR8IDH1IDH2KDM4E
SCHEMBL15290157 0.97 CCR1 (0.46) CCR1CCR8IDH1IDH2KDM4E
Hydrochloric Acid SCHEMBL4381119 0.93 CCR1 (0.42) CCR1CCR8IDH1IDH2KDM4E
SCHEMBL15289847 0.89 CCR1 (0.39) CCR1CCR8IDH1IDH2KDM4E
SCHEMBL20348778 0.87 CCR1 (0.67) CCR1CCR8IDH1IDH2KDM4E
SCHEMBL42955 0.84 PGK1 (0.39) CCR1CCR8IDH1IDH2KDM4E
SCHEMBL25212251 0.83 KDM4E (0.63) CCR1CCR8KDM4ETDP1L3MBTL1
SCHEMBL7814795 0.82 MEN1 (0.60) KDM4ETDP1L3MBTL1LMNAHSP90AA1
SCHEMBL23457336 0.82 IDH1 (0.35) CCR1CCR8IDH1IDH2HTT
Hydrochloric Acid SCHEMBL30595152 0.81 PGK1 (0.38) CCR1CCR8IDH1IDH2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-20140275429-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING PLURALITY OF TYPES OF TRANSITION METAL CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-18 US disclosed