SCHEMBL16079341

SCHEMBL16079341

O=C(O)C1(O)CC2C(O)C(O)C2C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.35
GRM4 Q14833 5/20 0.33
AKR1B1 P15121 2/20 0.33
PTPN1 P18031 2/20 0.33
GRM8 O00222 2/20 0.33
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33
AKR1B10 O60218 1/20 0.33
APP P05067 1/20 0.33
G6PD P11413 1/20 0.33
EPHX2 P34913 1/20 0.33
CYP2C19 P33261 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GRM6 O15303 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinic Acid SCHEMBL10125264 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL39555 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL14960616 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL6656460 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL19490687 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL39556 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL614369 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL1286207 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL7923331 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP
Quinic Acid SCHEMBL12026338 0.81 HSD17B10 (0.39) APLNRAKR1B1PTPN1AKR1B10APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140274936-A1 COORDINATION COMPLEXES, PHARMACEUTICAL SOLUTIONS COMPRISING COORDINATION COMPLEXES, AND METHODS OF TREATING PATIENTS SYNTHONICS, INC. (US) 2014-09-18 US disclosed