Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.47 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16083945 | 1.00 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL23092965 | 0.78 | SKP2 (0.58) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3986115 | 0.74 | SKP2 (0.49) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL23114374 | 0.74 | SKP2 (0.49) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL16079472 | 0.71 | CYP3A4 (0.64) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL5720593 | 0.70 | CYP3A4 (0.55) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL5720594 | 0.70 | CYP3A4 (0.55) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL5838115 | 0.69 | SKP2 (0.68) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL23093089 | 0.68 | SKP2 (0.42) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL2475751 | 0.68 | NPC1 (0.62) | CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295667-B2 | Pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A inhibitor as an active ingredient | KOREA BASIC SCIENCE INSTITUTE (KR) | 2016-03-29 | — | — | US | disclosed |
| US-20140275198-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES OR FATTY LIVER CONTAINING A CYP4A INHIBITOR AS AN ACTIVE INGREDIENT | KOREA BASIC SCIENCE INSTITUTE (KR) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275198-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES OR FATTY LIVER CONTAINING A CYP4A INHIBITOR AS AN ACTIVE INGREDIENT | CYP4A11, CYP4A22, CYP7A1 | CYP3A4 11/4885CYP2D6 105/4885CYP2C9 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.