Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753063 | 0.85 | EPHX1 (0.35) | EPHX1HTR2CSLC6A4GAACTSS | |
| SCHEMBL1424706 | 0.85 | EPHX1 (0.35) | EPHX1HTR2CSLC6A4GAACTSS | |
| SCHEMBL4971663 | 0.83 | EPHX1 (0.33) | EPHX1HTR2CSLC6A4GAACTSS | |
| SCHEMBL4971669 | 0.83 | EPHX1 (0.33) | EPHX1HTR2CSLC6A4GAACTSS | |
| SCHEMBL14666763 | 0.81 | ADH1B (0.38) | EPHX1GAACTSSCTSKHPGD | |
| SCHEMBL4972424 | 0.78 | EPHX1 (0.33) | EPHX1GAACTSSCTSKTSHR | |
| SCHEMBL647264 | 0.78 | TSHR (0.37) | EPHX1GAACTSSCTSKBTK | |
| SCHEMBL9744375 | 0.78 | TSHR (0.37) | EPHX1GAACTSSCTSKBTK | |
| SCHEMBL4328796 | 0.78 | TSHR (0.37) | EPHX1GAACTSSCTSKBTK | |
| SCHEMBL2712968 | 0.78 | TSHR (0.37) | EPHX1GAACTSSCTSKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110082132-A1 | [4-(1-AMINO-EHTYL) - CYCLOHEXYL] -METHYL-AMINE AND [6-(1-AMINO-EHTYL) -TETRAHYDRO-PYRAN-3-YL] -METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082132-A1 | [4-(1-AMINO-EHTYL) - CYCLOHEXYL] -METHYL-AMINE AND [6-(1-AMINO-EHTYL) -TETRAHYDRO-PYRAN-3-YL] -METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS | DOT1L, EHMT1, Q6ZSR9 | EPHX1 840/4885HTR2C 967/4885SLC6A4 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.