Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GZMB | P10144 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9925820 | 1.00 | GZMB (0.82) | GZMB | |
| SCHEMBL9904580 | 0.90 | GZMB (0.66) | GZMB | |
| SCHEMBL16053479 | 0.90 | GZMB (0.66) | GZMB | |
| SCHEMBL21186459 | 0.90 | GZMB (0.83) | GZMB | |
| SCHEMBL15485596 | 0.90 | GZMB (0.83) | GZMB | |
| SCHEMBL22697207 | 0.90 | GZMB (0.83) | GZMB | |
| SCHEMBL30431008 | 0.90 | GZMB (0.83) | GZMB | |
| SCHEMBL9925812 | 0.89 | GZMB (0.79) | GZMB | |
| SCHEMBL9925685 | 0.87 | GZMB (0.78) | GZMB | |
| SCHEMBL9925813 | 0.87 | GZMB (0.77) | GZMB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139014-A1 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF VASCULAR ENDOTHELIAL GROWTH FACTOR ACTIVITY AND VASCULAR PERMEABILITY | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-09-18 | — | — | WO | disclosed |