Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 18/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16049804 | 0.90 | PKLR (0.65) | PKLR | |
| SCHEMBL16051036 | 0.73 | PKLR (0.59) | PKLR | |
| SCHEMBL21976020 | 0.71 | PKLR (0.51) | PKLR | |
| SCHEMBL16084068 | 0.69 | PKLR (1.00) | PKLR | |
| SCHEMBL16084037 | 0.69 | PKLR (1.00) | PKLR | |
| SCHEMBL16049744 | 0.67 | PKLR (1.00) | PKLR | |
| SCHEMBL16083896 | 0.67 | PKLR (1.00) | PKLR | |
| SCHEMBL16130053 | 0.66 | PKLR (0.80) | PKLR | |
| SCHEMBL16084066 | 0.66 | PKLR (1.00) | PKLR | |
| SCHEMBL16084023 | 0.65 | PKLR (0.78) | PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139144-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |