Mannitol

Mannitol

SCHEMBL1608397

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nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
TDP1 Q9NUW8 1/20 0.65
KDM4E B2RXH2 2/20 0.46
PDE4A P27815 1/20 0.46
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
MGAM O43451 2/20 0.33
MAPT P10636 1/20 0.33
TOP1 P11387 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL8952346 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL2087831 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL29111380 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL9446139 0.97 LMNA (0.65) LMNAL3MBTL1TDP1KDM4EPDE4A
Adonitol SCHEMBL27524057 0.94 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL5516463 0.94 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL8860951 0.92 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL28102593 0.92 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL28118472 0.87 LMNA (0.52) LMNAL3MBTL1TDP1KDM4EPDE4A
E968 SCHEMBL5923897 0.87 LMNA (0.47) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2309523-A1 Solid conductive polymer electrolytic capacitor and method for producing same comprising a drying step Shin-Etsu Polymer Co. Ltd. (JP) 2011-04-13 EP disclosed
US-20110080690-A1 SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PRODUCING SAME SHIN-ETSU POLYMER CO., LTD. (JP) 2011-04-07 US disclosed
WO-2000042133-A1 IMPROVED FUEL COMPOSITIONS INFINEUM INTERNATIONAL LTD (GB) 2000-07-20 WO disclosed
US-4946686-A Solubility modulated drug delivery system MERCK & CO., INC. (US) 1990-08-07 US disclosed
EP-0099198-B1 IMPROVEMENTS IN OR RELATING TO THE CURING OF EPOXIDE RESINS THOMAS SWAN AND CO., LTD. (GB) 1987-03-11 EP disclosed
US-4305857-A Process for the preparation of stable dispersions of polyisocyanate-polyaddition products in hydroxyl containing compounds BAYER AKTIENGESELLSCHAFT (DE) 1981-12-15 US disclosed