Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 18/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16083890 | 0.82 | PKLR (0.69) | PKLR | |
| SCHEMBL21976614 | 0.82 | PKLR (0.52) | PKLRMEN1KMT2AALDH1A1 | |
| SCHEMBL16049669 | 0.81 | PKLR (0.77) | PKLR | |
| SCHEMBL16083831 | 0.78 | PKLR (0.69) | PKLR | |
| SCHEMBL16084075 | 0.77 | PKLR (0.69) | PKLR | |
| SCHEMBL21976611 | 0.71 | PKLR (0.59) | PKLR | |
| SCHEMBL16083758 | 0.71 | PKLR (0.86) | PKLR | |
| SCHEMBL21977201 | 0.69 | PKLR (0.68) | PKLR | |
| SCHEMBL21976496 | 0.68 | PKLR (0.58) | PKLR | |
| SCHEMBL16084045 | 0.68 | PKLR (0.72) | PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139144-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014139325-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |