Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365390 | 0.87 | S1PR1 (0.56) | S1PR1PLA2G4BTDP1KDM4EMAPK1 | |
| SCHEMBL2197581 | 0.84 | S1PR1 (0.53) | S1PR1PLA2G4BTDP1KDM4EMAPK1 | |
| SCHEMBL382120 | 0.84 | PLA2G4B (0.55) | S1PR1PLA2G4BKDM4ETSHRADRB2 | |
| SCHEMBL6231558 | 0.84 | PLA2G4B (0.55) | S1PR1PLA2G4BKDM4ETSHRADRB2 | |
| SCHEMBL21990 | 0.84 | PLA2G4B (0.55) | S1PR1PLA2G4BKDM4ETSHRADRB2 | |
| SCHEMBL9797717 | 0.84 | PLA2G4B (0.55) | S1PR1PLA2G4BKDM4ETSHRADRB2 | |
| SCHEMBL9797915 | 0.84 | PLA2G4B (0.55) | S1PR1PLA2G4BKDM4ETSHRADRB2 | |
| SCHEMBL5080243 | 0.84 | PLA2G4B (0.52) | S1PR1PLA2G4BTDP1KDM4EMAPK1 | |
| SCHEMBL5713089 | 0.81 | S1PR1 (0.50) | S1PR1PLA2G4BTDP1KDM4EMAPK1 | |
| SCHEMBL6071806 | 0.81 | MAPT (0.69) | S1PR1PLA2G4BTSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110080458-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, INC. | 2011-04-07 | — | — | US | disclosed |
| US-7704667-B2 | Dyes and use thereof in imaging members and methods | ZINK IMAGING, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| WO-2009097433-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, INC. (US) | 2009-08-06 | — | — | WO | disclosed |
| US-20080187866-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, LLC | 2008-08-07 | — | — | US | disclosed |
| US-20070224552-A1 | PROCESS FOR THE PREPARATION OF NOVEL DYES FOR USE IN IMAGING MEMBERS | ZINK IMAGING, LLC | 2007-09-27 | — | — | US | disclosed |
| US-7220868-B2 | Process for the preparation of novel dyes for use in imaging members | ZINK IMAGING, LLC (US) | 2007-05-22 | — | — | US | disclosed |
| US-20060234143-A1 | Process for the preparation of novel dyes for use in imaging members | ZINK IMAGING, LLC | 2006-10-19 | — | — | US | disclosed |
| US-7008759-B2 | Dyes and use thereof in imaging members and methods | POLAROID CORPORATION (US) | 2006-03-07 | — | — | US | disclosed |
| US-20040191668-A1 | Novel dyes and use thereof in imaging members and methods | ZINK HOLDINGS LLC | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187866-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | CACYBP, KLHDC2, ZKSCAN2 | S1PR1 3619/4885PLA2G4B 2879/4885TDP1 1950/4885 |
| US-20070224552-A1 | PROCESS FOR THE PREPARATION OF NOVEL DYES FOR USE IN IMAGING MEMBERS | CACYBP, ZKSCAN2, CRYAB | S1PR1 3424/4885PLA2G4B 4005/4885TDP1 2352/4885 |
| US-20110080458-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | CACYBP, KLHDC2, ZKSCAN2 | S1PR1 3619/4885PLA2G4B 2879/4885TDP1 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.