Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 19/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.50 |
| ▸ | OXTR | P30559 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16087505 | 1.00 | AVPR1A (0.50) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL16087513 | 0.91 | AVPR1A (0.62) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL2585593 | 0.88 | OXTR (0.56) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL2588113 | 0.88 | OXTR (0.56) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL2585590 | 0.88 | OXTR (0.56) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL16087561 | 0.87 | AVPR1A (0.47) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL16087519 | 0.87 | AVPR1A (0.47) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL11890017 | 0.85 | AVPR1A (0.51) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL16774898 | 0.85 | AVPR1A (0.47) | AVPR1AKCNH2OXTRAVPR2 | |
| SCHEMBL16087524 | 0.84 | AVPR1A (0.49) | AVPR1AKCNH2OXTRAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569319-B1 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | HOFFMANN LA ROCHE (CH) | 2014-09-24 | — | — | EP | claimed |