Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609763 | 0.90 | PDE10A (0.47) | ALDH1A1HSD17B10SMN1; SMN2PDE10ALMNA | |
| SCHEMBL1610305 | 0.89 | PDE10A (0.44) | ALDH1A1HSD17B10SMN1; SMN2PDE10ALMNA | |
| SCHEMBL1610382 | 0.89 | PDE10A (0.44) | ALDH1A1HSD17B10SMN1; SMN2PDE10ALMNA | |
| SCHEMBL1609068 | 0.89 | PDE10A (0.44) | ALDH1A1HSD17B10SMN1; SMN2PDE10APDE4A | |
| SCHEMBL1610277 | 0.89 | PDE10A (0.44) | ALDH1A1HSD17B10SMN1; SMN2PDE10APDE4A | |
| SCHEMBL1609687 | 0.89 | PDE10A (0.45) | ALDH1A1HSD17B10SMN1; SMN2PDE10APDE4A | |
| SCHEMBL1609110 | 0.87 | HPGD (0.50) | ALDH1A1HSD17B10SMN1; SMN2PDE10AHPGD | |
| SCHEMBL1609556 | 0.87 | KDM4E (0.43) | ALDH1A1HSD17B10SMN1; SMN2PDE10AMAPK1 | |
| SCHEMBL1609781 | 0.87 | ABL1 (0.45) | ALDH1A1HSD17B10SMN1; SMN2PDE10A | |
| SCHEMBL1609704 | 0.87 | PDE10A (0.62) | ALDH1A1PDE10APDE4ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | ALDH1A1 1562/4885HSD17B10 1869/4885SMN1; SMN2 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.