Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610988 | 0.90 | HPGD (0.40) | HPGDNPSR1SLC6A3P2RX7PDE10A | |
| SCHEMBL1608875 | 0.87 | ALDH1A1 (0.51) | HPGDSLC6A3PDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL1609147 | 0.85 | PDE10A (0.50) | HPGDNPSR1SLC6A3PDE10AALDH1A1 | |
| SCHEMBL1609253 | 0.84 | NTRK1 (0.40) | P2RX7PDE10AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1610289 | 0.84 | ADORA3 (0.39) | PDE10APRKCQ | |
| SCHEMBL12712720 | 0.83 | PDE10A (0.49) | PDE10A | |
| SCHEMBL1609762 | 0.83 | MAPT (0.44) | HPGDNPSR1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL13769165 | 0.83 | PDE10A (0.40) | HPGDPDE10AALDH1A1 | |
| SCHEMBL12712820 | 0.83 | PDE10A (0.40) | HPGDNPSR1PDE10A | |
| SCHEMBL1609687 | 0.83 | PDE10A (0.45) | SLC6A3PDE10AALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | HPGD 1668/4885NPSR1 2070/4885SLC6A3 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.