Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9593456 | 0.93 | CXCR4 (0.47) | CXCR4SMN1; SMN2PARP1 | |
| SCHEMBL2917496 | 0.93 | — | — | |
| Piperazine SCHEMBL28212300 | 0.93 | CXCR4 (0.37) | CXCR4PARP1LTA4H | |
| SCHEMBL2971314 | 0.93 | — | — | |
| SCHEMBL14407772 | 0.93 | CXCR4 (0.37) | CXCR4PARP1LTA4H | |
| SCHEMBL946397 | 0.93 | — | — | |
| SCHEMBL2276644 | 0.93 | — | — | |
| SCHEMBL7260250 | 0.93 | CXCR4 (0.37) | CXCR4PARP1LTA4H | |
| SCHEMBL5329747 | 0.93 | CXCR4 (0.37) | CXCR4PARP1LTA4H | |
| Hydrochloric Acid SCHEMBL31589175 | 0.91 | CXCR4 (0.36) | CXCR4PARP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259999-B1 | MATERIALS FOR THE SOLID/LIQUID EXTRACTION OF HEAVY METAL IONS, CONTAINING SUPPORTED N-FUNCTIONALISED POLYAZACYCLOALKANES | CENTRE NAT RECH SCIENT (FR) | 2018-06-27 | — | — | EP | disclosed |
| US-8975395-B2 | Materials for the solid/liquid extraction of heavy metal ions, containing supported N-functionalized polyazacycloalkanes | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-03-10 | — | — | US | disclosed |
| US-20110079557-A1 | MATERIALS FOR THE SOLID/LIQUID EXTRACTION OF HEAVY METAL IONS, CONTAINING SUPPORTED N-FUNCTIONALIZED POLYAZACYLOALKANES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2011-04-07 | — | — | US | disclosed |
| US-7312327-B2 | Method of preparing nitrogen macrocycles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2007-12-25 | — | — | US | disclosed |
| US-7312327-B2 | Method of preparing nitrogen macrocycles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2007-12-25 | — | — | US | disclosed |
| US-7312327-B2 | Method of preparing nitrogen macrocycles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2007-12-25 | — | — | US | disclosed |
| US-20040206940-A1 | Novel method of preparing nitrogen macrocycles | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2004-10-21 | — | — | US | disclosed |
| EP-1430036-A1 | NOVEL METHOD OF PREPARING NITROGEN MACROCYCLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003029228-A1 | NOVEL METHOD OF PREPARING NITROGEN MACROCYCLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110079557-A1 | MATERIALS FOR THE SOLID/LIQUID EXTRACTION OF HEAVY METAL IONS, CONTAINING SUPPORTED N-FUNCTIONALIZED POLYAZACYLOALKANES | NR2C2, NR2E3, NCOR2 | CXCR4 1224/4885SMN1; SMN2 3538/4885PARP1 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.