⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260250 | 1.00 | CXCR4 (0.37) | — | |
| Piperazine SCHEMBL28212300 | 1.00 | CXCR4 (0.37) | — | |
| SCHEMBL2971314 | 1.00 | — | — | |
| SCHEMBL2276644 | 1.00 | — | — | |
| SCHEMBL14407772 | 1.00 | CXCR4 (0.37) | — | |
| SCHEMBL5329747 | 1.00 | CXCR4 (0.37) | — | |
| Hydrochloric Acid SCHEMBL31589175 | 0.97 | CXCR4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL29749088 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL20339645 | 0.97 | CXCR4 (0.36) | — | |
| SCHEMBL1608965 | 0.93 | CXCR4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12558648-B2 | Amine compound, acid gas absorbent, method for removing acid gas, and acid gas removal apparatus | KABUSHIKI KAISHA TOSHIBA (JP) | 2026-02-24 | — | — | US | claimed |
| CN-114672538-B | Method for improving stability of alkaline detection reagent in bottle opening | 潍坊三维生物工程集团有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-20240092791-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-21 | — | — | US | claimed |
| EP-4263549-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-10-25 | — | — | EP | claimed |
| CN-114349711-B | Synthesis method of (R) -1-Boc-3-hydroxymethyl piperazine | 四川依维欣医药科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| EP-4182032-A1 | HYDROISOQUINOLINE OR HYDRONAPHTHYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2023-05-24 | — | — | EP | claimed |
| CN-115835910-A | Hydrogenated isoquinoline or naphthyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-114672538-A | Method for improving bottle opening stability of alkaline detection reagent | 潍坊三维生物工程集团有限公司 | 2022-06-28 | — | — | CN | claimed |
| WO-2022128848-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-06-23 | — | — | WO | claimed |
| CN-114349711-A | Synthesis method of (R) -1-Boc-3-hydroxymethyl piperazine | 四川恒康科技发展有限公司 | 2022-04-15 | — | — | CN | claimed |
| WO-2016184829-A1 | DUAL NK-1/NK-3 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SEX-HORMONE-DEPENDENT DISEASES | NERRE THERAPEUTICS LIMITED (GB) | 2016-11-24 | — | — | WO | claimed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | claimed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | claimed |
| EP-2796442-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2014-10-29 | — | — | EP | claimed |
| EP-1727526-A2 | PIPERAZINE UREA DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | Schering Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | claimed |
| WO-2005079769-A2 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-09-01 | — | — | WO | claimed |
| US-6846827-B1 | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2005-01-25 | — | — | US | claimed |
| EP-1226126-B1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-01-05 | — | — | EP | claimed |
| EP-1226126-A1 | PYRIMIDINE DERIVATIVES | AstraZeneca AB (SE) | 2002-07-31 | — | — | EP | claimed |
| WO-2001027089-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-19 | — | — | WO | claimed |