SCHEMBL16089799

SCHEMBL16089799

c1cc(-c2cccc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)c2)cc(-c2cccc(-c3ccc4c5ccccc5c5ccccc5c4c3)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 2/20 0.52
KDM4E B2RXH2 1/20 0.52
KMT2A Q03164 3/20 0.36
IL1R1 P14778 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 2/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 1/20 0.36
FAAH O00519 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PKM P14618 1/20 0.35
MGLL Q99685 1/20 0.35
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33
TSPO P30536 1/20 0.33
HDAC4 P56524 1/20 0.33
FOLH1 Q04609 1/20 0.33
GAA P10253 1/20 0.33
RXRA P19793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16089829 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL16089791 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL30103631 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL16089790 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL16089827 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL16089818 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL16089838 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL16089794 0.98 ATM (0.50) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL16089800 0.98 ATM (0.50) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL12494273 0.98 L3MBTL1 (0.53) L3MBTL1ATMKDM4EKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9831437-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-28 US disclosed
US-9831437-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-28 US disclosed
EP-2866273-B1 Organic electrolumiescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-10-18 EP disclosed
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-10-27 US disclosed
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-10-27 US disclosed
US-9419225-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-08-16 US disclosed
US-9419225-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-08-16 US disclosed
EP-2866273-A1 Organic electrolumiescent materials and devices Universal Display Corporation (US) 2015-04-29 EP disclosed
US-20150053938-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-02-26 US disclosed
US-20140264292-A1 HOST COMPOUNDS FOR PHOSPHORESCENT OLEDS AND DEVICES THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2014-09-18 US disclosed
US-20140264292-A1 HOST COMPOUNDS FOR PHOSPHORESCENT OLEDS AND DEVICES THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2014-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CCNL2, INTS9, SRSF9 L3MBTL1 215/4885ATM 2663/4885KDM4E 2938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.