Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23415410 | 0.79 | LPAR1 (0.42) | HCAR3SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30593394 | 0.78 | LPAR1 (0.41) | HCAR3SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29904796 | 0.78 | HCAR3 (0.52) | HCAR3SMN1; SMN2CYP2C19HTTPDE10A | |
| SCHEMBL5555518 | 0.76 | HCAR3 (0.42) | HCAR3SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30797267 | 0.74 | HCAR3 (0.43) | HCAR3LPAR1IRAK4MAPKAPK2KDR | |
| SCHEMBL13103478 | 0.73 | HCAR3 (0.62) | HCAR3CYP2D6PDE10ACDK2CDC7 | |
| SCHEMBL16160635 | 0.73 | CYP1A2 (0.55) | HCAR3SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17623017 | 0.73 | HCAR3 (0.44) | HCAR3CYP1A2CYP2D6CYP2C19PDE10A | |
| SCHEMBL20355865 | 0.73 | KDR (0.37) | SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21360101 | 0.72 | CYP1A2 (0.57) | HCAR3SMN1; SMN2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144169-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |