Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 5/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17623436 | 0.83 | TP53 (0.40) | HCAR3TP53ACACBRAB9AKDM4E | |
| SCHEMBL16090980 | 0.77 | TP53 (0.42) | HCAR3TP53ACACBRAB9AKDM4E | |
| SCHEMBL16090970 | 0.77 | TP53 (0.42) | HCAR3TP53ACACBRAB9AKDM4E | |
| SCHEMBL17622955 | 0.73 | TP53 (0.36) | HCAR3TP53RAB9AKDM4EMEN1 | |
| SCHEMBL16090928 | 0.72 | TP53 (0.38) | HCAR3TP53ACACBRAB9AKDM4E | |
| SCHEMBL17622843 | 0.71 | TP53 (0.38) | HCAR3TP53RAB9AKDM4EMEN1 | |
| SCHEMBL17623016 | 0.71 | TP53 (0.32) | TP53RAB9AKDM4EMEN1NPC1 | |
| SCHEMBL16091163 | 0.69 | TP53 (0.45) | HCAR3TP53ACACBRAB9AKDM4E | |
| SCHEMBL16091174 | 0.68 | TP53 (0.43) | HCAR3TP53ACACBRAB9AKDM4E | |
| SCHEMBL17623352 | 0.66 | TP53 (0.41) | HCAR3TP53ACACBRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144169-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |