Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 8/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091163 | 0.80 | TP53 (0.45) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL16091174 | 0.77 | TP53 (0.43) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL16090980 | 0.75 | TP53 (0.42) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL16090970 | 0.75 | TP53 (0.42) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL17623034 | 0.74 | TP53 (0.38) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL17623255 | 0.73 | TP53 (0.39) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL17623436 | 0.72 | TP53 (0.40) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL16090918 | 0.70 | TP53 (0.47) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL17622955 | 0.70 | TP53 (0.36) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL17622705 | 0.69 | KDM1A (0.44) | TP53KDM4EMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |