Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091909 | 0.88 | APP (0.54) | APPMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL16183132 | 0.86 | APP (0.51) | APPMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL20380850 | 0.76 | APP (0.55) | APPMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL16091914 | 0.75 | APP (0.56) | APPMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL16183126 | 0.74 | APP (0.57) | APPMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL16183127 | 0.72 | APP (0.55) | APPMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL27953870 | 0.71 | KDM4E (0.64) | MEN1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL16091912 | 0.71 | KDM4E (0.48) | MEN1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL13745868 | 0.70 | APP (0.61) | APPMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL13091019 | 0.70 | APP (0.54) | APPMEN1POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210063405-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2021-03-04 | — | — | US | disclosed |
| US-10024863-B2 | Methods for dye selection for protein melt temperature determinations | Life Technologies Corporation (US) | 2018-07-17 | — | — | US | disclosed |
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |
| WO-2014144360-A2 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation (US) | 2014-09-18 | — | — | WO | disclosed |