Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16093004 | 0.91 | GLP1R (0.37) | GLP1RTSHRCASP1CASP7HSD17B10 | |
| SCHEMBL16093019 | 0.82 | GLP1R (0.41) | GLP1RC3AR1 | |
| SCHEMBL16093009 | 0.81 | GLP1R (0.38) | GLP1RC3AR1 | |
| SCHEMBL22300759 | 0.81 | GLP1R (0.37) | GLP1RALDH1A1KMT2A | |
| SCHEMBL22300367 | 0.80 | GLP1R (0.36) | GLP1RSELPKMT2A | |
| SCHEMBL25454947 | 0.78 | TLR2 (0.39) | GLP1RTSHRPOLBKMT2A | |
| SCHEMBL19375656 | 0.78 | GLP1R (0.44) | GLP1RTSHRALDH1A1C3AR1 | |
| SCHEMBL15002870 | 0.78 | GLP1R (0.57) | GLP1RSELPC3AR1 | |
| SCHEMBL25454946 | 0.78 | GLP1R (0.38) | GLP1RKISS1RPOLBKMT2A | |
| SCHEMBL13640991 | 0.77 | GLP1R (0.41) | GLP1RTSHRCASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841249-B2 | Growth hormones with prolonged in-vivo efficacy | NOVO NORDISK A/S (DK) | 2014-09-23 | — | — | US | disclosed |