Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16093019 | 0.97 | GLP1R (0.41) | GLP1RTLR2C3AR1NOD1SIRT2 | |
| SCHEMBL26425890 | 0.92 | GLP1R (0.48) | GLP1RTLR2C3AR1SIRT2ALB | |
| SCHEMBL16093004 | 0.91 | GLP1R (0.37) | GLP1RTLR2C3AR1NOD1SIRT2 | |
| SCHEMBL19069621 | 0.85 | GLP1R (0.42) | GLP1RTLR2C3AR1NOD1SIRT2 | |
| SCHEMBL25454947 | 0.81 | TLR2 (0.39) | GLP1RTLR2NOD1SIRT2ALB | |
| SCHEMBL16093436 | 0.81 | GLP1R (0.38) | GLP1RC3AR1 | |
| SCHEMBL25664162 | 0.81 | GLP1R (0.43) | GLP1RTLR2C3AR1ALBSIRT5 | |
| SCHEMBL17903320 | 0.80 | GLP1R (0.41) | GLP1RC3AR1ALBSIRT5 | |
| SCHEMBL16093006 | 0.78 | CES2 (0.41) | GLP1RTLR2NOD1CYP1A2CYP3A4 | |
| SCHEMBL14217291 | 0.78 | L3MBTL1 (0.51) | C3AR1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841249-B2 | Growth hormones with prolonged in-vivo efficacy | NOVO NORDISK A/S (DK) | 2014-09-23 | — | — | US | disclosed |
| US-8841249-B2 | Growth hormones with prolonged in-vivo efficacy | NOVO NORDISK A/S (DK) | 2014-09-23 | — | — | US | disclosed |