Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100279 | 0.76 | CYP1A2 (0.41) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL10351592 | 0.70 | GAA (0.64) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL195416 | 0.67 | ALDH1A1 (0.74) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL14848863 | 0.66 | GAA (0.58) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL2454385 | 0.65 | CYP2C9 (0.47) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL14792955 | 0.65 | ALDH1A1 (0.55) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL30600424 | 0.65 | GAA (0.57) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL30471152 | 0.64 | GAA (0.56) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL14841972 | 0.64 | GAA (0.56) | L3MBTL1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL21625777 | 0.64 | GAA (0.56) | L3MBTL1GAATDP1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970220-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153235-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |