Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 14/20 | 0.66 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16093779 | 0.85 | HASPIN (0.71) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL16099097 | 0.84 | HASPIN (0.45) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL2565027 | 0.84 | HASPIN (0.49) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL16098852 | 0.82 | HASPIN (0.45) | HASPINDYRK2MAOAMAOBDYRK1A | |
| SCHEMBL16098887 | 0.81 | HASPIN (0.66) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL16094165 | 0.80 | HASPIN (0.41) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL30939953 | 0.80 | HASPIN (1.00) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL12286389 | 0.80 | HASPIN (1.00) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL16099839 | 0.78 | HASPIN (0.39) | HASPINDYRK2TP53CYP1A2CYP3A4 | |
| SCHEMBL16099605 | 0.77 | EPHX2 (0.41) | HASPINALOX15DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |