Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 15/20 | 0.50 |
| ▸ | PDE4A | P27815 | 15/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610459 | 0.99 | CHRM3 (0.52) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1609597 | 0.94 | PDE10A (0.46) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1610275 | 0.85 | PDE10A (0.57) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1609810 | 0.84 | PDE10A (0.56) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1610199 | 0.82 | PDE10A (0.53) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1610047 | 0.79 | PDE10A (0.49) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL12738422 | 0.75 | PDE10A (0.55) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL2470158 | 0.75 | PDE10A (0.57) | PDE10APDE4BPDE4D | |
| SCHEMBL719516 | 0.75 | TDP1 (0.47) | PDE10APDE4BPDE4D | |
| SCHEMBL12738156 | 0.74 | CHRM3 (0.54) | PDE10ACHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885CHRM3 2705/4885PDE4A 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.