Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 17/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469864 | 0.92 | PDE10A (0.48) | PDE10ATLR8 | |
| SCHEMBL2464501 | 0.90 | PDE10A (0.46) | PDE10ATLR8 | |
| SCHEMBL1611084 | 0.78 | PDE10A (0.60) | PDE10APDE4BPDE4D | |
| SCHEMBL1609892 | 0.78 | PDE10A (0.54) | PDE10APDE4BPDE4D | |
| SCHEMBL1609597 | 0.77 | PDE10A (0.46) | PDE10APDE4BPDE4D | |
| SCHEMBL1611392 | 0.77 | PDE10A (0.44) | PDE10AALDH1A1PDE4BPDE4D | |
| SCHEMBL1609122 | 0.75 | PDE10A (0.48) | PDE10APDE4BPDE4D | |
| SCHEMBL1609883 | 0.75 | PDE10A (0.43) | PDE10AALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL1609398 | 0.75 | PDE10A (0.54) | PDE10APDE4BPDE4D | |
| SCHEMBL1610459 | 0.74 | CHRM3 (0.52) | PDE10APDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2369931-A2 | HERBICIDE/SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | claimed |
| WO-2010060578-A2 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | claimed |
| EP-2191720-A1 | Herbicide-safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | claimed |
| EP-2369931-A2 | HERBICIDE/SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060578-A2 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191720-A1 | Herbicide-safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |