Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512713 | 0.86 | FGFR1 (0.36) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL10496372 | 0.85 | POLG (0.47) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL76047 | 0.85 | POLG (0.47) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL1144357 | 0.85 | POLG (0.44) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL26123976 | 0.84 | POLG (0.47) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL1629582 | 0.79 | FGFR1 (0.44) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL28265099 | 0.75 | POLG (0.37) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL28406825 | 0.75 | LMNA (0.47) | POLGPOLBP2RY2P2RY4P2RY6 | |
| Triphosphate SCHEMBL27974998 | 0.74 | POLG (0.49) | POLGFGFR1POLBSLC22A6P2RY2 | |
| SCHEMBL7743090 | 0.73 | POLG (0.40) | POLGFGFR1POLBSLC22A6P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2971033-B1 | MANUFACTURING METHODS FOR PRODUCTION OF RNA TRANSCRIPTS | MODERNA THERAPEUTICS INC (US) | 2019-05-29 | — | — | EP | disclosed |
| US-20190085368-A1 | MANUFACTURING METHODS FOR PRODUCTION OF RNA TRANSCRIPTS | MODERNA THERAPEUTICS, INC. | 2019-03-21 | — | — | US | disclosed |
| US-10138507-B2 | Manufacturing methods for production of RNA transcripts | MODERNATX, INC. (US) | 2018-11-27 | — | — | US | disclosed |
| US-20160024547-A1 | MANUFACTURING METHODS FOR PRODUCTION OF RNA TRANSCRIPTS | ARES CAPITAL CORPORATION, AS AGENT | 2016-01-28 | — | — | US | disclosed |
| EP-2971033-A1 | MANUFACTURING METHODS FOR PRODUCTION OF RNA TRANSCRIPTS | Moderna Therapeutics, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014152027-A1 | MANUFACTURING METHODS FOR PRODUCTION OF RNA TRANSCRIPTS | MODERNA THERAPEUTICS, INC. (US) | 2014-09-25 | — | — | WO | disclosed |