Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 16/20 | 0.65 |
| ▸ | KDM5A | P29375 | 6/20 | 0.65 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095409 | 0.85 | KDM4C (0.65) | KDM4CKDM5APHF8KDM5BKDM2B | |
| SCHEMBL16095072 | 0.84 | KDM4C (0.65) | KDM4CKDM5APHF8KDM5B | |
| SCHEMBL16095025 | 0.81 | KDM4C (0.65) | KDM4CKDM5APHF8KDM5BKDM2B | |
| SCHEMBL16095232 | 0.80 | KDM4C (0.48) | KDM4CKDM5AKDM5BKDM2B | |
| SCHEMBL16094315 | 0.79 | KDM4C (0.65) | KDM4CKDM5APHF8KDM5BKDM2B | |
| SCHEMBL16033611 | 0.79 | KDM4C (1.00) | KDM4CKDM5APHF8KDM5BKDM2B | |
| SCHEMBL16095912 | 0.78 | KDM4C (0.61) | KDM4CKDM5APHF8KDM5BKDM2B | |
| SCHEMBL16095348 | 0.78 | KDM4C (0.63) | KDM4CKDM5APHF8KDM5BKDM2B | |
| SCHEMBL16102028 | 0.78 | KDM4C (0.44) | KDM4CKDM5APHF8KDM5BEPHX2 | |
| SCHEMBL16095234 | 0.77 | PHF8 (0.40) | KDM4CKDM5APHF8KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |