Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 17/20 | 0.63 |
| ▸ | KDM5A | P29375 | 7/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095409 | 0.91 | KDM4C (0.65) | KDM4CKDM5AKDM5BPHF8KDM2B | |
| SCHEMBL16095912 | 0.88 | KDM4C (0.61) | KDM4CKDM5AKDM5BPHF8KDM2B | |
| SCHEMBL16095163 | 0.86 | KDM4C (0.62) | KDM4CKDM5AKDM5BPHF8KDM2B | |
| SCHEMBL16095025 | 0.82 | KDM4C (0.65) | KDM4CKDM5AKDM5BPHF8KDM2B | |
| SCHEMBL16094315 | 0.82 | KDM4C (0.65) | KDM4CKDM5AKDM5BPHF8KDM2B | |
| SCHEMBL16095072 | 0.82 | KDM4C (0.65) | KDM4CKDM5AKDM5BPHF8 | |
| SCHEMBL16095265 | 0.80 | KDM4C (0.62) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16095232 | 0.79 | KDM4C (0.48) | KDM4CKDM5AKDM5BKDM2B | |
| SCHEMBL16095179 | 0.79 | KDM4C (0.61) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16095032 | 0.78 | KDM4C (0.65) | KDM4CKDM5AKDM5BPHF8KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |