Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.49 |
| ▸ | KDM5A | P29375 | 5/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095178 | 0.79 | KDM4C (0.36) | KDM4C | |
| SCHEMBL16095318 | 0.72 | KDM4C (0.52) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16095534 | 0.68 | KDM4C (0.62) | KDM4CKDM2B | |
| SCHEMBL16095141 | 0.67 | KDM4C (0.61) | KDM4CKDM2BKDM5A | |
| SCHEMBL16095092 | 0.67 | KDM4C (0.63) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16034477 | 0.66 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16034019 | 0.66 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16103405 | 0.66 | KDM4C (0.52) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16095046 | 0.64 | KDM4C (0.60) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16095837 | 0.63 | KDM4C (0.36) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |