Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095178 | 0.84 | KDM4C (0.36) | KDM4CKCNH2KCNA5GRM5 | |
| SCHEMBL16095604 | 0.82 | KDM4C (0.36) | KDM4CKCNH2GRM5JAK2TYK2 | |
| SCHEMBL17604548 | 0.76 | NPY5R (0.38) | KDM4CKCNH2GRM5 | |
| SCHEMBL16100266 | 0.72 | IDH1 (0.36) | KDM4CKCNH2GRM5 | |
| SCHEMBL16100476 | 0.70 | MAPK14 (0.41) | KCNH2 | |
| SCHEMBL16095481 | 0.69 | KDM4C (0.57) | KDM4C | |
| SCHEMBL16094914 | 0.69 | HRH3 (0.36) | KDM4CKCNH2 | |
| SCHEMBL16033875 | 0.69 | NPY5R (0.38) | KDM4CKCNH2GRM5 | |
| SCHEMBL17604615 | 0.68 | NPY5R (0.44) | KCNH2 | |
| SCHEMBL16095353 | 0.67 | NPY5R (0.35) | KDM4CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |