Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.62 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 4/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095179 | 0.89 | KDM4C (0.61) | KDM4CKDM5BKDM4AKDM5AKDM2B | |
| SCHEMBL16095163 | 0.83 | KDM4C (0.62) | KDM4CKDM5BKDM5AKDM2BMRGPRX4 | |
| SCHEMBL16095912 | 0.82 | KDM4C (0.61) | KDM4CKDM5BKDM5AKDM2B | |
| SCHEMBL16095348 | 0.80 | KDM4C (0.63) | KDM4CKDM5BKDM4AKDM5AKDM2B | |
| SCHEMBL16095072 | 0.79 | KDM4C (0.65) | KDM4CKDM5BKDM5AMRGPRX4 | |
| SCHEMBL16033236 | 0.76 | KDM4C (1.00) | KDM4CKDM5BKDM4AKDM5AKDM2B | |
| SCHEMBL16095166 | 0.76 | PARP1 (0.45) | KDM4CKDM5BKDM4A | |
| SCHEMBL16095409 | 0.76 | KDM4C (0.65) | KDM4CKDM5BKDM5AKDM2B | |
| SCHEMBL16095540 | 0.75 | GRM5 (0.43) | MRGPRX4 | |
| SCHEMBL19628752 | 0.75 | KDM4C (0.81) | KDM4CKDM5BKDM4AKDM5AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |