Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 5/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KDM5C | P41229 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.40 |
| ▸ | KDM4A | O75164 | 4/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102028 | 0.88 | KDM4C (0.44) | EPHX2KDM5AKDM5BKDM4EKDM5C | |
| SCHEMBL16095770 | 0.87 | KDM5B (0.45) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL16095346 | 0.87 | KDM4C (0.52) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL16094676 | 0.80 | KDM5A (0.49) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL16095328 | 0.79 | KDM4C (0.43) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL16033753 | 0.77 | KDM5A (0.60) | KDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL16094521 | 0.77 | KDM5B (0.59) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL16095193 | 0.75 | KDM4C (0.59) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL20978930 | 0.75 | EPHX2 (0.41) | EPHX2KDM5AKDM5BKDM4EKDM5C | |
| SCHEMBL16095432 | 0.74 | KDM5B (0.50) | KDM5AKDM5BKDM4EKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |