Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 7/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.48 |
| ▸ | KDM4A | O75164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | KDM5C | P41229 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.39 |
| ▸ | KDM6B | O15054 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104961 | 0.84 | KDM5B (0.55) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16095770 | 0.81 | KDM5B (0.45) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16095346 | 0.81 | KDM4C (0.52) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16095331 | 0.80 | KDM2B (0.55) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16095329 | 0.80 | EPHX2 (0.45) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16095045 | 0.79 | KDM5B (0.48) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16095432 | 0.78 | KDM5B (0.50) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16094674 | 0.78 | KDM4C (0.48) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16095089 | 0.77 | KDM5B (0.62) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL16033557 | 0.75 | KDM5A (0.74) | KDM5AKDM5BKDM4CKDM4AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |