Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 10/20 | 0.48 |
| ▸ | KDM5A | P29375 | 8/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.47 |
| ▸ | KDM4A | O75164 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 4/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.38 |
| ▸ | KDM4B | O94953 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095275 | 0.90 | KDM4C (0.49) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16095045 | 0.89 | KDM5B (0.48) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16094674 | 0.86 | KDM4C (0.48) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16104961 | 0.82 | KDM5B (0.55) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16094676 | 0.80 | KDM5A (0.49) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16095431 | 0.77 | KDM5B (0.41) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16034926 | 0.76 | KDM5A (0.73) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16095206 | 0.76 | KDM4C (0.64) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16095328 | 0.75 | KDM4C (0.43) | KDM2BKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16095345 | 0.74 | KDM4C (0.44) | KDM5BKDM5AKDM4CKDM4AKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |