SCHEMBL16096000

SCHEMBL16096000

Nc1nc(Cl)nc(C(F)(F)F)c1[N+](=O)[O-]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.33
HPGD P15428 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
HIF1A Q16665 1/20 0.33
TXNRD1 Q16881 1/20 0.33
TXNRD3 Q86VQ6 1/20 0.33
TXNRD2 Q9NNW7 1/20 0.33
MAPT P10636 5/20 0.32
MGMT P16455 3/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 3/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HTT P42858 2/20 0.31
TP53 P04637 1/20 0.31
XBP1 P17861 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15218852 0.82 TSHR (0.35) ALDH1A1TSHRHPGDTDP1CYP3A4
SCHEMBL257010 0.81 ALDH1A1 (0.38) ALDH1A1TSHRHPGDTDP1MAPT
SCHEMBL29978776 0.76 MAPT (0.35) ALDH1A1TSHRHPGDTDP1MAPT
SCHEMBL2459982 0.76 MAPT (0.35) ALDH1A1TSHRHPGDTDP1MAPT
SCHEMBL16123449 0.76 MAPT (0.37) ALDH1A1TSHRHPGDTDP1MAPT
SCHEMBL16096211 0.76 CYP1A2 (0.38) ALDH1A1HPGDTDP1MAPTKMT2A
SCHEMBL25366611 0.73 ALDH1A1 (0.42) ALDH1A1TSHRHPGDTDP1CYP3A4
SCHEMBL16123533 0.73 CFTR (0.38) ALDH1A1TSHRALOX15MAPTMGMT
SCHEMBL166184 0.73 MAPT (0.48) ALDH1A1HPGDTDP1MAPTKMT2A
SCHEMBL31224694 0.71 ALDH1A1 (0.30) ALDH1A1TSHRHPGDALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014149208-A1 PURINE-BASED PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2014-09-25 WO disclosed