Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601359 | 0.81 | USP2 (0.42) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL20265001 | 0.79 | USP2 (0.46) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL2600436 | 0.75 | USP2 (0.40) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL31552232 | 0.74 | HPGD (0.40) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL1838102 | 0.73 | PREP (0.37) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL31551926 | 0.72 | HPGD (0.42) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL28856336 | 0.71 | CHRM2 (0.38) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| Hydrochloric Acid SCHEMBL28241841 | 0.71 | PREP (0.36) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL795243 | 0.70 | USP2 (0.42) | USP2SMN1; SMN2ESR2CTSKNR1H2 | |
| SCHEMBL3277549 | 0.70 | USP2 (0.46) | USP2SMN1; SMN2ESR2CTSKNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014151630-A2 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | IRM LLC (BM) | 2014-09-25 | — | — | WO | disclosed |