Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27423893 | 0.90 | USP2 (0.44) | USP2SMN1; SMN2RECQLESR2CTSK | |
| SCHEMBL9185491 | 0.82 | USP2 (0.41) | USP2SMN1; SMN2RECQLESR2CTSK | |
| SCHEMBL29550355 | 0.80 | TSHR (0.31) | MEN1KMT2A | |
| SCHEMBL3921646 | 0.78 | USP2 (0.38) | USP2SMN1; SMN2RECQL | |
| SCHEMBL1601359 | 0.73 | USP2 (0.42) | USP2SMN1; SMN2RECQLESR2CTSK | |
| SCHEMBL315722 | 0.72 | USP2 (0.54) | USP2SMN1; SMN2RECQLESR2CTSK | |
| SCHEMBL28898488 | 0.72 | USP2 (0.39) | USP2SMN1; SMN2RECQLESR2CTSK | |
| SCHEMBL25373469 | 0.71 | CHRM2 (0.42) | USP2SMN1; SMN2RECQLCTSKHPGD | |
| SCHEMBL30805636 | 0.71 | USP2 (0.38) | USP2SMN1; SMN2RECQLESR2CTSK | |
| SCHEMBL29162611 | 0.71 | USP2 (0.38) | USP2SMN1; SMN2RECQLESR2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302886-A | Triazolopyridazine derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| US-7696349-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-1689760-B1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF SE (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-20090227801-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-10 | — | — | US | disclosed |
| EP-2057109-A2 | ADDITION REACTIONS USING TRANSITION METAL CATALYSTS IN HALOGENATED SOLVENTS | BASF SE (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-7442842-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2008-10-28 | — | — | US | disclosed |
| WO-2008046918-A2 | ADDITION REACTIONS USING TRANSITION METAL CATALYSTS IN HALOGENATED SOLVENTS | BASF SE (DE) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008031889-A2 | PNICOGEN-CONTAINING PSEUDOCHELATING LIGANDS | BASF SE (DE) | 2008-03-20 | — | — | WO | disclosed |
| EP-1807437-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-18 | — | — | EP | disclosed |
| US-20070073092-A1 | Method for asymmetric synthesis | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-29 | — | — | US | disclosed |
| EP-1689760-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-16 | — | — | EP | disclosed |
| WO-2006045597-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | BASF AKTIENGESELLSCHAFT (DE) | 2006-05-04 | — | — | WO | disclosed |
| WO-2005051964-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073092-A1 | Method for asymmetric synthesis | COASY, PIN1, INF2 | USP2 2693/4885SMN1; SMN2 4690/4885RECQL 3736/4885 |
| US-20090227801-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | PFKFB3, PHPT1, PFKFB4 | USP2 4396/4885SMN1; SMN2 4838/4885RECQL 3684/4885 |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | COASY, PIN1, INF2 | USP2 2693/4885SMN1; SMN2 4690/4885RECQL 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.