Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.48 |
| ▸ | KDM5C | P41229 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KDM6B | O15054 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.46 |
| ▸ | KDM5A | P29375 | 4/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 4/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095566 | 0.81 | KDM4C (0.61) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16094928 | 0.80 | KDM5C (0.55) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16095741 | 0.78 | KDM4C (0.60) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16094521 | 0.77 | KDM5B (0.59) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16095193 | 0.77 | KDM4C (0.59) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16096062 | 0.76 | KDM4C (0.54) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16104961 | 0.75 | KDM5B (0.55) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16033607 | 0.75 | KDM5A (0.74) | KDM4CKDM5BKDM5AKDM2BKDM4A | |
| SCHEMBL16095331 | 0.74 | KDM2B (0.55) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL16094800 | 0.74 | KDM4C (0.61) | KDM4CKDM5CKDM4EKDM6BKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |