Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.60 |
| ▸ | PYGL | P06737 | 12/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107375 | 0.84 | KDM4E (0.47) | PYGLKDM4EMEN1NPC1RAB9A | |
| SCHEMBL6398667 | 0.84 | MAPT (0.67) | FLT3KDM4EMEN1NPC1RAB9A | |
| SCHEMBL1608132 | 0.83 | PYGL (0.57) | PYGLHRH4HRH3 | |
| SCHEMBL6162398 | 0.82 | PYGL (0.69) | PYGLHRH4HRH3 | |
| SCHEMBL1608140 | 0.82 | PYGL (0.59) | PYGLHRH4HRH3MEN1KMT2A | |
| SCHEMBL1608567 | 0.81 | GUSB (0.60) | PYGLHRH4HRH3 | |
| SCHEMBL3253089 | 0.78 | PYGL (0.67) | FLT3PYGLHRH4HRH3 | |
| SCHEMBL4919678 | 0.78 | FLT3 (0.61) | FLT3PYGLHRH4HRH3KDM4E | |
| SCHEMBL5891883 | 0.78 | PYGL (0.67) | PYGLHRH4HRH3 | |
| SCHEMBL23014105 | 0.78 | KMT2A (0.60) | KDM4EMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086885-A1 | Indole-2-carboxylic acid amides | PROSIDION LIMITED (GB) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086885-A1 | Indole-2-carboxylic acid amides | IDO2, IDO1, CPT1A | FLT3 2303/4885PYGL 152/4885HRH4 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.