Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096599 | 1.00 | GRIN2B (0.42) | GRIN2BGRIN1SMN1; SMN2LMNACLK2 | |
| SCHEMBL16096272 | 0.87 | GRIN1 (0.32) | GRIN2BGRIN1 | |
| SCHEMBL16096233 | 0.87 | KDM4E (0.42) | SMN1; SMN2LMNATDP1MTNR1AMTNR1B | |
| SCHEMBL16096615 | 0.87 | GRIN1 (0.32) | GRIN2BGRIN1 | |
| SCHEMBL16096271 | 0.87 | GRIN1 (0.32) | GRIN2BGRIN1 | |
| SCHEMBL16095182 | 0.78 | GRIN2B (0.44) | GRIN2BGRIN1SMN1; SMN2LMNACLK2 | |
| SCHEMBL16095180 | 0.78 | GRIN2B (0.44) | GRIN2BGRIN1SMN1; SMN2LMNACLK2 | |
| SCHEMBL16098219 | 0.77 | MAPT (0.43) | GRIN2BGRIN1SMN1; SMN2LMNATDP1 | |
| SCHEMBL16098217 | 0.77 | MAPT (0.43) | GRIN2BGRIN1SMN1; SMN2LMNATDP1 | |
| SCHEMBL17499731 | 0.76 | GRIN2B (0.42) | GRIN2BGRIN1SMN1; SMN2LMNACLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |