Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499560 | 0.87 | GRIN1 (0.32) | GRIN2BGRIN1MEN1KMT2A | |
| SCHEMBL17499612 | 0.86 | GRIN1 (0.32) | GRIN2BGRIN1MEN1KMT2A | |
| SCHEMBL17499153 | 0.84 | SMN1; SMN2 (0.45) | GRIN2BGRIN1MEN1KMT2AKDM4E | |
| SCHEMBL17499814 | 0.84 | GRIN2B (0.44) | GRIN2BGRIN1GAAMEN1KMT2A | |
| SCHEMBL17499298 | 0.78 | ALDH1A1 (0.44) | GRIN2BGRIN1GAAMEN1KMT2A | |
| SCHEMBL16096597 | 0.76 | GRIN2B (0.42) | GRIN2BGRIN1NPC1KDM4EPOLB | |
| SCHEMBL16096599 | 0.76 | GRIN2B (0.42) | GRIN2BGRIN1NPC1KDM4EPOLB | |
| SCHEMBL16095180 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN1GAANPC1LMNA | |
| SCHEMBL16095182 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN1GAANPC1LMNA | |
| SCHEMBL17499730 | 0.74 | KMT2A (0.39) | MEN1KMT2ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |