⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634723 | 0.78 | TSHR (0.72) | — | |
| SCHEMBL339534 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL11463456 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL29195613 | 0.77 | ALDH1A1 (0.62) | — | |
| Formaldehyde SCHEMBL2873057 | 0.75 | ALDH1A1 (0.83) | — | |
| SCHEMBL10001 | 0.74 | — | — | |
| SCHEMBL28060459 | 0.74 | ALDH1A1 (1.00) | — | |
| SCHEMBL49917 | 0.74 | — | — | |
| SCHEMBL3040611 | 0.74 | — | — | |
| SCHEMBL597385 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018180-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | AJINOMOTO CO., INC. (JP) | 2024-01-18 | — | — | US | disclosed |
| EP-4293035-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | AJINOMOTO CO., INC. (JP) | 2023-12-20 | — | — | EP | disclosed |
| CN-112007045-A | Chiral control | 波涛生命科学有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-104661664-B | Chiral control | 波涛生命科学有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-111050806-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2020-04-21 | — | — | CN | disclosed |
| EP-3016964-A1 | METHOD FOR INCORPORATING PROTECTING ACETAL AND ACETAL ESTER GROUPS, AND ITS APPLICATION FOR THE PROTECTION OF HYDROXYL FUNCTION | Instytut Chemii Bioorganicznej Polskiej Akademii Nauk (PL) | 2016-05-11 | — | — | EP | disclosed |
| WO-2014148928-A1 | METHOD FOR INCORPORATING PROTECTING ACETAL AND ACETAL ESTER GROUPS, AND ITS APPLICATION FOR THE PROTECTION OF HYDROXYL FUNCTION | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2014-09-25 | — | — | WO | disclosed |